Axel GANSMULLER

Axel GANSMULLER


Maître de Conférences




telephone+33 (0)3 72 74 52 58


fax+33 (0)3 83 68 43 47


courrielaxel.gansmuller@univ-lorraine.fr



carriere_icn Carrière:


since 12/2011: Associate Professor , lecturer at département Génie Biologie Santé (GBS) from the IUT Nancy Brabois
Researcher at the CRM2 laboratory (Pr. D. Schaniel) in the NMR methodology development team

2009 – 2011: Postdoctoral Researcher, Institute of structural biology, Grenoble, Pr B. Brutscher, “ NMR characterization of structure and dynamics of the bacterial cell wall »

2005 – 2008: Postdoctoral Researcher, Magnetic Resonance Laboratory of Southampton University, Southampton, Pr. M. H. Levitt. “NMR characterization of the first photointermediates of the GPCR Rhodopsin” & “SSNMR methodology developments for selective dipolar recoupling in solids”

2001 – 2004: Doctoral Researcher, TECTOSPIN, Université de Versailles, Pr. F. Taulelle, “Double quantum NMR study of elastomer compatibility” (for MICHELIN company)



recherche_icn Domaine de recherche:


– Résonance Magnétique Nucléaire en solution et à l’état solide
– Photo-RMN in-situ
– Résonance Quadrupolaire Nucléaire
– Calcul DFT de paramètres RMN, RQN et IR
 

Thématiques de recherche:

 
Mes recherches se concentrent principalement sur le développement de la technique de spectroscopie de résonance nucléaire (RMN en solide et solution, RQN) afin d’établir et de comprendre les liens entre la structure moléculaire et les propriétés des matériaux. L’originalité de notre approche réside dans la combinaison des techniques de RMN du solide et de RMN en solutions, avec les informations obtenues par diffraction totale des rayon X couplé à l’analyse des fonctions de distribution de paires (PDF). Afin de pouvoir interpréter plus en détails les mesures RMN, en termes de structure et de dynamique, j’utilise le calcul quantique par DFT (Density Functional Theory) qui permet d’établir des modèles structuraux et de simuler des observables RMN ainsi que des spectres Infra Rouge. J’ai récemment démarré une nouvelle thématique de recherche portant sur la caractérisation par « photo-RMN » de composés photo-commutables. Dans ce cadre nous développons des approches in-situ et ex-situ en solution et en solide pour étudier par RMN la structure des états photoinduits.
 
 

Thématiques de recherche

 
 
Détail des 3 principales thématiques de recherche:
 
Caractérisation dynamique et structurale de matériaux hétérogènes.pdf
Caractérisation par « photo-RMN » de composés photo-commutables.pdf
Méthodologie et instrumentation en Résonance Quadripolaire Nucléaire.pdf




publication_icn Publications:


Gansmuller A., Mikhailov A. A., Kostin G. A., Raya J., Palin C., Woike T. and Schaniel D.
Solid-State Photo-NMR Study on Light-Induced Nitrosyl Linkage Isomers Uncovers Their Structural, Electronic, and Diamagnetic Nature
Analytical Chemistry 94(10) (2022) 4474-4483 DOI link

Rjiba A., Khoder H., Jelassi J., Bouguet-Bonnet S., Gardiennet C., Bendeif E.-E., Gansmuller A., Dorbez-Sridi R.
Differential scanning calorimetry and NMR study of water confined in a mesoporous bioactive glass
Microporous and Mesoporous Materials 316 (2021) 110992 DOI link

Angelini G., Gansmuller A., Pécourneau J., Gasbarri C.
An insight into cyclocurcumin cis-trans isomerization: Kinetics in solution and in the presence of silver nanoparticles
Journal of Molecular Liquids 333 (2021) 116000 DOI link

Mikhailov A. A. , Woike T., Gansmuller A., Schaniel D., Kostin G. A.
Photoinduced linkage isomers in a model ruthenium nitrosyl complex: Identification and assignment of vibrational modes
Spectrochimica Acta, Part A: Molecular Spectroscopy 263 (2021) 120217 DOI link

Berro Y., Gueddida S., Bouizi Y., Bellouard C., Bendeif E.-E., Gansmuller A., Celzard A., Fierro V., Ihiawakrim D., Ersen O., Kassir M., El Haj Hassan F., Lebegue S., Badawi M., Canilho N., Pasc A.
Imprinting isolated single iron atoms onto mesoporous silica by templating with metallosurfactants
Journal of Colloid and Interface Science 573 (2020) 193-203 DOI link

Ajili W., Laurent G. P., Menguy N., Gansmuller A., Huchette S., Auzoux-Bordenave S., Nassif N., and Azais T.
Chemical Heterogeneities within the Disordered Mineral domains of Aragonite Platelets in Nacre from the European Abalone Haliotis tuberculata
Journal of Physical Chemistry C 124(26) (2020) 14118-14130 DOI link

Haffner F., Canilho N., Medronho B., Gardiennet C., Gansmuller A., Pasc A.
In situ follow-up of hybrid alginate-silicate microbeads formation by linear rheology
Physical Chemistry Chemical Physics (2018) DOI link

Deligey F., Bouguet-Bonnet S., Doudouh A., Marande P.-L., Schaniel D., Gansmüller A.
Bridging Structural and Dynamical Models of a Confined Sodium Nitroprusside Complex
The Journal of Physical Chemistry C (2018) DOI link

Wathier L., Venet T., Thomas A., Nunge H., Bonfanti E., Cosnier F., Parietti-Winkler C., Campo P., Tsan P., Bouguet-Bonnet S., Gansmüller A.
Membrane fluidity does not explain how solvents act on the middle-ear reflex
NeuroToxicology 57 (2016) 13-21 DOI link

Bendeif E.-E., Gansmuller A., Hsieh K.-Y., Pillet S., Woike T., Zobel M., Neder R., Bouazaoui M., El Hamzaoui H., Schaniel D.
Structure determination of molecular nanocomposites by combining pair distribution function analysis and solid-state NMR
RSC Advances 5 (2015) 8895-8902 DOI link

Hsieh K.-Y., Bendeif E.-E., Gansmuller A., Pillet S., Woike T., Schaniel D.
Structure and dynamics of guest molecules confined in a mesoporous silica matrix: Complementary NMR and PDFcharacterisation
RSC Advances 3 (2013) 26132-26141 DOI link

Gansmuller A., Simorre J.-P., Hediger S.
Windowed R-PDLF recoupling: A flexible and reliable tool to characterize molecular dynamics
Journal of Magnetic Resonance 234 (2013) 154-164 DOI link

McLean N., Gansmuller A., Concistre M., Brown L., Levitt M., Brown R.
Syntheses of 13C2-labelled 11Z-retinals
Tetrahedron 67 (2011) 8404-8410 DOI link

Gansmuller, A., Concistrè, M., McLean, N., Johannessen, O., Marín-Montesinos, I., Bovee-Geurts, P., Verdegem, P., Lugtenburg, J., Brown, R., DeGrip, W., Levitt, M.
Towards an interpretation of 13C chemical shifts in bathorhodopsin, a functional intermediate of a G-protein coupled receptor
1788 (2009) 1350-1357 DOI link

Concistrè, M., Gansmuller, A., McLean, N., Johannessen, O., Mari?n Montesinos, I., Bovee-Geurts, P., Brown, R., DeGrip, W., Levitt, M.
Light Penetration and Photoisomerization in Rhodopsin studied by Numerical Simulations and Double-Quantum Solid-State NMR Spectroscopy
Journal of the American Chemical Society 131 (2009) 6133-6140 DOI link

Pileio, G., Mamone, S., Mollica, G., Montesinos, I., Gansmuller, A., Carravetta, M., Brown, S., Levitt, M.
Estimation of internuclear couplings in the solid-state NMR of multiple-spin systems. Selective spin echoes and off-magic-angle sample spinning
Chemical Physics Letters 456 (2008) 116-121 DOI link

Concistrè, M., Gansmuller, A., McLean, N., Johannessen, O., Mari?n Montesinos, I., Bovee-Geurts, P., Verdegem, P., Lugtenburg, J., Brown, R., DeGrip, W., Levitt, M.
Double-Quantum 13 C Nuclear Magnetic Resonance of Bathorhodopsin, the First Photointermediate in Mammalian Vision
Journal of the American Chemical Society 130 (2008) 10490-10491 DOI link

Giuseppe Pileio, Maria Concistrè, Neville McLean, Axel Gansmüller, Richard C. D. Brown, and Malcolm H. Levitt
Analytical theory of γ-encoded double-quantum recoupling sequences in solid-state nuclear magnetic resonance
Journal of Magnetic Resonance 186(1) (2007) 65-74 DOI link

Marin-Montesinos, I., Mollica, G., Carravetta, M., Gansmuller, A., Pileio, G., Bechmann, M., Sebald, A., Levitt, M.
Truncated dipolar recoupling in solid-state nuclear magnetic resonance
Chemical Physics Letters 432 (2006) 572-578 DOI link

Lai, W., McLean, N., Gansmuller, A., Verhoeven, M., Antonioli, G., Carravetta, M., Duma, L., Bovee-Geurts, P., Johannessen, O., de Groot, H., Lugtenburg, J., Emsley, L., Brown, S., Brown, R., DeGrip,
Accurate Measurements of 13 C? 13 C J -Couplings in the Rhodopsin Chromophore by Double-Quantum Solid-State NMR Spectroscopy
Journal of the American Chemical Society 128 (2006) 3878-3879 DOI link

Beitone, L., Marrot, J., Loiseau, T., Férey, G., Henry, M., Huguenard, C., Gansmuller, A., Taulelle, F.
MIL-50, an Open-Framework GaPO with a Periodic Pattern of Small Water Ponds and Dry Rubidium Atoms:  a Combined XRD, NMR, and Computational Study
Journal of the American Chemical Society 125 (2003) 1912-1922 DOI link

Beitone, L., Huguenard, C., Gansmuller, A., Henry, M., Taulelle, F., Loiseau, T., Férey, G.
Order-Disorder in the Super-Sodalite Zn 3 Al 6 (PO 4 ) 12 , 4 t ren , 17H 2 O (MIL-74):  A Combined XRD?NMR Assessment
Journal of the American Chemical Society 125 (2003) 9102-9110 DOI link